Rethinking Cancer: Inside Thomas Seyfried’s Lab
A few weeks ago, my dad, my son and I had the opportunity to visit Professor Thomas Seyfried and his research team at Boston College. Three generation road trip, Jacob, Ralph and Ben Moss. We’ve...
Repurposed Drugs
Targeting Cancer’s Metabolic Achilles’ Heel
In November 2025, I traveled to Budapest, Hungary, to visit and interview research scientist Dr. Christos Chinopoulos at Semmelweis University. Join me as we discuss mitochondrial and metabolic...
Mitochondrial and Metabolic Theory of Cancer – Prof. Thomas Seyfried
This Podcast contains many scientific terms. To assist our readers in understanding them, we have created this glossary. What if cancer isn’t primarily a genetic disease — but a metabolic one? In...
From Parasites to Pathways: Antiparasitic Drugs in Cancer
In alternative medicine, it is not uncommon for someone to propose a sweeping idea that is overstated yet contains a kernel of truth. The medical establishment, eager to highlight flaws, often...
S5 E2 – Ivermectin & Cancer – Hype vs. Science
https://youtu.be/LVj4BIP3CP8 Is there real science behind the hype? Ivermectin, best known as an antiparasitic drug, has sparked interest for its potential anticancer properties. While...
Cancer Stem Cells
Transcript Another huge topic that cancer patients should know about are cancer stem cells. Cancer stem cells are well known to the research community. There are 17,000 journal articles in the...
The Other Half of Cancer Treatment with Will LaValley, MD
In this episode of The Moss Report Podcast, Ralph Moss speaks with Will LaValley, MD, about his personalized approach to treating cancer. Dr. LaValley is a leading practitioner of Molecular...
Repurposed Drugs for Cancer with Raymond Chang, M.D.
In this episode of The Moss Report Podcast, Ralph W. Moss, Ph.D. speaks with Raymond Chang, M.D. about integrative oncology. Dr. Chang has long been a champion of off-label or repurposed...
Is Personalized Medicine the Future of Cancer Treatment? A Conversation with Dr. Nagourney
In this episode of The Moss Report Podcast, Ralph W. Moss speaks with Dr. Robert Nagourney about his well-documented approach to precision oncology. Nagourney's strategy takes a step away from...
Repurposed Drugs
Transcript There's a category of treatments for cancer that the average person knows nothing about. It's called repurposed drugs. And what that means is that there are, of course, thousands of...
Repurposed and Off-Label Drugs
FDA Approved Agents “Repurposed drugs” are agents that have been approved by the U.S. Food and Drug Administration (FDA) or its equivalent in other countries but are being redeployed (without...
Is this One Dollar Pill a Breast Cancer Breakthrough?
Can this pill save lives? A one dollar pill may prevent many early relapses and deaths from breast cancer. It also may work on some other common form of cancers. This is the suggestion of some...
Metformin for Cancer
Repurposed to Target Cancer Stem Cells Metformin is the most widely prescribed oral drug for type 2 diabetes (T2D) in the world. It is included on the World Health Organization’s list of...
Cimetidine (Tagamet®)
Cimetidine (Tagamet®)Cimetidine (Tagamet®) is a powerful antacid, which is used to treat indigestion and/or stomach ulcers. It was originally a prescription drug but eventually became generic and...
Aspirin
May Reduce the Risk of RecurrenceAt the present time, it is increasingly apparent that one of the world’s most common drugs, aspirin, can also have a powerfully retardant effect on cancer,...
Insulin Potentiated Therapy IPT
IPT and Low Dose ChemotherapyInsulin potentiated therapy (IPT) refers to the use of insulin as an adjunct to low-dose chemotherapy. The doctors at the ChemoThermia Oncology Center in Istanbul use...
Repurposed Drugs for Cancer Stem Cells
A Very Promising Area of Study There are various repurposed drugs that target cancer stem cells (CSCs). These include metformin, doxycycline, mebendazole, thioridazine, disulfiram, statins,...
Aspirin – A Cautionary Tale
Unexpected Developments and DangersOne of the most unexpected developments of recent years has been the emergence of aspirin (acetylsalicylic acid) as a cancer preventative. The idea of using...
Galectin-3 and Cancer
Role of Galectin-3 and Modified Citrus PectinGalectin-3 is a proteinGalectin-3 is a protein whose production is encoded by one particular gene (called LGALS3). It is one of 14 lectins that have...
Ketorolac – Toradol®
A Remarkable Discovery There has been a remarkable discovery concerning the effect on cancer relapse of a common prescription drug, ketorolac (Toradol®). Michael W. Retsky, Ph.D. formerly of the...
Metformin May Boost Survival in Ovarian Cancer
Herb Derived Drug Metformin is a drug commonly used to treat type 2 diabetes. It decreases the amount of circulating glucose in the blood. Since cancers mainly feed on glucose, there has been...
Tetrathiomolybdate
Lowering Copper Levels in the BloodAmmonium Tetrathiomolybdate (T.M.) is a drug that inhibits the development of new blood vessels in cancer by lowering levels of the common mineral copper in the...
Antifungal Medicine, Itraconazole vs. Cancer
Increasing Interest in Sporanox There is merit in the idea of Food and Drug Administration (FDA)-approved medications repurposed for use against cancer. For example, there is increasing interest...
Celecoxib Celebrex®
The Use of COX-2 Inhibitors is in DoubtThe FDA approved the use of celecoxib (Celebrex®), one of a class of so-called COX-2 inhibitors, which is used in the treatment of rheumatoid and...
Bisphosphonates
A Dual BenefitBisphosphonates are a class of drugs that prevent the damage that cancer can inflict (such as bone resorption) to the skeletal structure. A randomized, double-blind study of...