Ascites and Abdominal Cavity Metastases
The peritoneum is a smooth and transparent membrane that lines the cavity of the abdomen and encloses the various abdominal and pelvic organs. Cancer can arise in this cavity, usually by...
Conventional Medicine
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Metastatic Cancer- Poole and Watson
A Tale of Two Papers Poole and Watson I would like to contrast the mainstream media's reception of the papers of E.M. Poole and her colleagues with the opposing views on antioxidants of Nobel...
The EMT Transition
The So-Called Epithelial-To-Mesenchymal Transition (EMT).One standard explanation of metastasis is the epithelial to mesenchymal transition (EMT). Mesenchymal cells are undifferentiated loose...
Does CHOP cause Metastases in NHL?
The Problem of Second Cancers Along with increased survival as a result of increasingly effective treatment in NHL, there is growing evidence that some treatment regimens themselves cause cancer....
Bone Metastases
Treatments Cancer of many kinds can spread to the bones from elsewhere in the body. In fact, bone metastases are by far the most common cause of cancer within the bones of the skeleton. Generally...
Lung and Liver Metastases
Laser Ablation Since 1996, Alex Rolle, MD, Chief of Thoracic and Vascular Surgery in Coswig/Dresden, Germany has been performing aggressive laser ablations of lung metastases. He has removed an...
Brain Metastases
A Major Health Problem Brain metastases were once believed to be very rare. However, because of the increased use of sophisticated diagnostic techniques such as CT and MRI scans it is now...
Treatment of Liver Metastases
Primary Signs The liver is the central headquarters for the maintenance and cleansing of the blood. It is provided with an extremely rich blood supply. In essence, the liver can be conceived of...
Can Chemotherapy Destroy Circulating Tumor Cells (CTCs)?
A Crucial QuestionA CTC is a ‘Circulating Tumor Cell’. There is a crucial question of whether chemotherapy can destroy CTCs. Breast cancerIn a big study of women with breast cancer, CTCs were...
Chemotherapy and Lung Cancer
Study Shows Negative Results Adding chemotherapy to radiation therapy does not prolong survival in operable, non-small-cell lung cancer, according to a large, randomized study published in the...
SEF Chemotherapy Mesna Mesnex
Not a Common View of ChemotherapySEF or Side Effect Free Chemotherapy® is a proposed treatment from Kenneth Matsumura, MD, of the Berkeley Institute International, in Berkeley, California. They...
Acute Myeloid Leukemia (AML) Specialists
List of AML Specialists The best way to find a specialist who treats acute myeloid leukemia (AML)—other than the time-tested method of word of mouth— is to consult the U.S.News.com website....
Oxaliplatin 3-Month Regimen
Many oncologists are now offering a 3-month regimen of oxaliplatin (OX) as a compromise, especially when OX is combined with oral capecitabine (Xeloda®, the oral prodrug form of 5-FU). This cuts...
Some Problems with Chemotherapy
Weighing the Benefits Many people criticize chemotherapy for its deficiencies. For instance, it is common knowledge that chemo can cause serious adverse effects, some of which oncologists cannot...
Chemo for Life?
Long Term Treatments There is an emerging trend in oncology to keep patients on anticancer drugs for longer periods, even years at a stretch. This concept was given support from two studies...
Chronobiology
Greater Benefit and Lower Risk The New York Times has discovered chronobiology, including chronomodulated chemotherapy. The science writer Olivia Judson, Ph.D., in the course of a column on...
Trifluridine and Tipiracil (Lonsurf®) for Metastatic Colorectal Cancer
The combination of trifluridine and tipiracil has been given the unusual name Lonsurf® (from Taiho Oncology). The US Food and Drug Administration (FDA) has approved a tablet combining these two...
Bazell Report on Anthracycline-Based Chemotherapy
An Outspoken CriticI read with interest a recent news report by Robert Bazell, NBC’s chief science and health correspondent. Bear in mind that Bazell has written a book on the development of the...
The Chemotherapy Concession Continues
The Side Hustle A recent study provided evidence that some oncologists prescribe chemotherapy based on their financial reward rather than the medical needs of their patients. This is a...
Acute Myeloid Leukemia (AML) and Treatment
Protecting Patients a PriorityIn order to carry off a successful treatment, it is sometimes necessary to hospitalize the patient during the period of “pancytopenia.” This is a condition in which...
Metronomic Chemo Offers Hope in Esophageal Cancer
Metronomic chemotherapy is being used in the U.S. with some preliminary success in difficult-to-treat cancers. Nick Chen, MD, Ph.D., an oncologist who serves as medical director of the Seattle...
HIPEC with Mitomycin and Oncothermia for Endometrial and Gynecologic Cancer
One treatment that has been used for stage IV endometrial cancer is heated intraperitoneal chemotherapy or HIPEC. According to French authors:“Seven patients are alive, four of them without...
Surrogate Markers
A Problem in OncologyOne of the most fundamental and problematic issues in oncology is that of so-called surrogate markers. “Local-regional control” of a tumor is basically a “surrogate marker”...
Modified Citrus Pectin Fights Cancer Metastases
Modified citrus pectin fights cancer metastases. This makes it potentially one of the most important substances in the complementary arsenal against cancer. MCP is a chemically altered form of...